Could infantile GERD be at end of a long chain of of events caused by impaired DNA Methylation? First things first; what is DNA Methylation? Without launching into a rather long and technical description, let’s just suffice it to say that it is critical to many fundamental cellular processes and it’s very bad when DNA Methylation does not function correctly. How bad? Impaired methylation has been implicated in the incidence of Rheumatoid arthritis, osteoarthritis, severe food allergies, cancer, HIV, mitochondrial disorders, Multiple Sclerosis, Parkinson’s, migraines, heavy metal accumulation, hormonal deficiencies, low thyroid, and infectious overgrowth such as viruses and Candida, as well as various Neuroimmune Disorders such as Autism, depression, and ADHD.
Of the myriad of symptoms which now seem to plague our infants, Gastroesophageal reflux disease (GERD) seems to remain among the most prevalent. And since we still don’t know the cause of infantile GERD, I thought I would investigate the potential link between it and DNA Methylation compromise. What a surprise when I discovered a number of studies which found that the treatment of GERD with melatonin, and a particular blend of vitamins and amino acids (all of which support methylation), improved GERD more effectively than the PPI medication Omeprazole (Prilosec)! And all without the side effects associated with suppressing one’s stomach acid.
Coincidence? Maybe, but I doubt it. I would certainly welcome additional research into this intriguing development. Perhaps infantile GERD may serve as an early-warning indicator of this silent, sneaky, and often debilitating condition.
- Regression of GI reflux disease symptoms using dietary supplementation with melatonin, vitamins, and amino acids: Comparison with Omeprazole
- Which is the best choice for gastroesophageal disorders: Melatonin or proton pump inhibitors?
- The Potential Therapeutic Effect of Melatonin in Gastroesophageal Reflux Disease